Table 1 The top platinum-resistance related genes based on text mining
From: Systematic analysis of ovarian cancer platinum-resistance mechanisms via text mining
Gene | Description | Count |
|---|---|---|
TP53 | tumor protein p53 | 108 |
ABCB1 | ATP binding cassette subfamily B member 1 | 64 |
AKT1 | AKT serine/threonine kinase 1 | 59 |
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit | 40 |
BCL2 | BCL2, apoptosis regulator | 28 |
EGFR | epidermal growth factor receptor | 27 |
BRCA1 | BRCA1, DNA repair associated | 26 |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 25 |
MAPK1 | mitogen-activated protein kinase 1 | 24 |
ABCC1 | ATP binding cassette subfamily C member 1 | 22 |
IL6 | interleukin 6 | 20 |
NFKB1 | nuclear factor kappa B subunit 1 | 20 |
STAT3 | signal transducer and activator of transcription 3 | 19 |
MTOR | mechanistic target of rapamycin kinase | 18 |
PARP1 | poly (ADP-ribose) polymerase 1 | 17 |
TNFSF10 | TNF superfamily member 10 | 17 |
BRCA2 | BRCA2, DNA repair associated | 15 |
HDAC1 | histone deacetylase 1 | 15 |
TNF | tumor necrosis factor | 15 |