Fig. 4From: NOTCH2 variant D1853H is mutated in two non-syndromic premature ovarian insufficiency patients from a Chinese pedigreeRNA-sequencing analysis of WT and Mut cells. (A) Heatmap data from the RNA-sequencing analysis of WT and Mut cells. The expression of 255 transcripts (including 106 protein-coding genes) was significantly different between the WT and Mut groups. Among them, 54 genes were downregulated and 52 genes were upregulated in the Mut group. (B) GO analysis of the 106 protein-coding genesBack to article page