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Table 3 Univariate and multivariate analyses of risk factors for pretreatment thrombocytosis.

From: Pretreatment thrombocytosis as an independent predictive factor for chemoresistance and poor survival in epithelial ovarian cancer

Factors

Platelet counts (×103/ mm3)

Univariate

Mutivariate

<  400 (n = 88)

≥ 400 (n = 38)

OR (95% CI)

P

OR (95% CI)

P

Microcytic hypochromic anemia

0.0022

 

0.0091

 Present

4 (4.6%)

7 (18.4%)

7.56 (2.04–36.23)

 

6.52 (1.57–36.73)

 

 Absent

84 (95.4%)

31 (81.6%)

Ref

 

Ref

 

FIGO stage

0.028

 

0.15

 I/ II

17 (19.3%)

2 (5.3%)

Ref

 

Ref

 

 III/ IV

71 (80.7%)

36 (94.7%)

4.31 (1.15–28.12)

 

2.84 (0.72–18.95)

 

Histologic subtype

0.061

 

 Serous

47 (53.4%)

27 (71.1%)

2.41 (0.97–5.00)

 

 

 Others*

41 (46.6%)

11 (28.9%)

Ref

 

 

Operation achievement

0.89

 

 Complete, Optimal

78 (88.6%)

34 (89.5%)

Ref

 

 

 Suboptimal

10 (11.4%)

4 (10.5%)

0.92 (0.24–2.96)

 

 

Non-malignant inflammatory condition

0.041

 

0.17

 Present

4 (4.6%)

6 (15.8%)

3.94 (1.06–16.27)

 

2.67 (0.085–1.56)

 

 Absent

84 (95.4%)

32 (84.2%)

Ref

 

Ref

 

TFI (months)

Mean ± SD

16.5 ± 23.03

8.30 ± 7.31

0.003 (0.00–0.30)

0.0091

0.0095 (0.00–0.75)

0.021

  1. *Endometorioid, mucinous, undifferentiated, or mixed type. Abbreviations: OR odds ratio, CI confidence interval, SD standard deviation, Hb hemoglobin, Ref reference, FIGO International Federation of Gynecology and Obstetrics, TFI treatment-free interval