First author (publication year) | Study design | Histology type | FIGO stage | Debulking Surgery | Group | Number of patients | Median age (y) | Definition of SL and USL |
---|---|---|---|---|---|---|---|---|
Harter (2019) [18] | RCT | Epithelial ovarian cancer | IIB–IV | R0 | SL | 323 | 60 | systematic pelvic and aortic lymphadenectomy |
USL | 324 | 60 | no lymphadenectomy | |||||
Maggioni (2006) [23] | RCT | Epithelial ovarian cancer | I–II | R1 | SL | 138 | 51 | systematic pelvic (≥20) and aortic (≥15) lymphadenectomy |
USL | 130 | 52 | random removal of pelvic and para-aortic LNs (sampling) | |||||
Panici (2005) [22] | RCT | Epithelial ovarian cancer | IIIB–IV | R1 | SL | 189 | 53 | systematic pelvic (≥25) and aortic (≥15) lymphadenectomy |
USL | 195 | 56 | bulky nodes only | |||||
Dell’ Anna (2012) [24] | RCT | Epithelial ovarian cancer | I–IV | R1 | SL | 158 | 50 | systematic pelvic (≥25) and aortic (≥15) lymphadenectomy |
USL | 150 | 52 | bulky nodes only |