Table 1 Clinico-pathological features of primary ovarian lesion in validation cohort: case dataset vs control dataset
Clinico-histopathological features validation cohort | Case Dataset n = 29 (%) | Control Dataset n = 19 (%) | pValue |
|---|---|---|---|
Age, median (years) [range] | 57 [39–76] | 52 [40–78] | N.S. |
Histological type | |||
 Serous | 25 (86) | 19 (100) | N.S. |
 Clear cell | 2 (7) |  | |
 Undifferentiated | 1 (3) |  | |
 Other | 1 (3) |  | |
Histological grade | |||
 G3 | 29 (100) | 19 (100) | N.S. |
FIGO stage | |||
 II | 2 (7) | 0 (0) | N.S. |
 III | 19 (65.5) | 13 (68) | |
 IV | 8 (27.5) | 6 (32) | |
Type of surgery | |||
 Upfront | 22 (76) | 8 (42) | 0.02 |
 Neoadjuvant CT + IDS | 7 (24) | 11 (58) | |
Macroscopic residual tumor | |||
 Present | 18 (62) | 6 (32) | 0.04 |
 Absent | 11 (38) | 13 (68) | |
First-line chemotherapy | |||
 Platinum-based | 29 (100) | 19 (100) | N.S. |
Relapse | |||
 Present | 29 (100) | 12 (63) | 0.0004 |
 Absent |  | 7 (37) | |
First site of relapse | |||
 CNS | 14 (48) | 0 (0) | 0.003 |
 Lymph nodes and / or peritoneum | 11 (38) | 11 (92)a | |
 Other | 4 (14) | 1 (8)a | |
Patient’s status | |||
 Alive | 7 (24) | 15 (79) | 0.0002 |
 Dead | 22 (76) | 4 (21) | |
PFS, median (months) [range] | 15 [0–62] | 17 [10–62] | N.S. |
OS, median (months) [range] | 48 [4–173] | 32 [19–78] | N.S. |