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Table 7 Immune-histochemical results and statistical analyses of AR considered as dichotomized variable as for both cases and controls datasets

From: Validation of Androgen Receptor loss as a risk factor for the development of brain metastases from ovarian cancers

IHC parameter

Cut-off

Case dataset (primary ovarian lesions) (%)

Control dataset (primary ovarian lesions) (%)

pValue (Cases vs controls: IHC comparison)

OR (Cases vs controls) (CI 95%)

 

AR

<  1%

7/39 (17.9)

2/40 (5)

0.087

  

≥ 1%

32/39 (82.1)

38/40 (95)

  

<  10%

26/39 (66.7)

7/40 (17.5)

< 0.001

9.429 (3.290–27.020)

 

≥ 10%

13/39 (33.3)

33/40 (82.5)

IRS ≤ 2

31/39 (79.5)

13/40 (32.5)

< 0.001

  

IRS > 2

8/39 (20.5)

27/40 (67.5)

  
  1. AR Androgen Receptor