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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Recent trends in stem cell therapy for premature ovarian insufficiency and its therapeutic potential: a review

Fig. 1

The morphological changes of ovary tissue by H&E and PCNA staining. Light microscopic examination of ovaries. H&E. (a-b) Normal ovary. (a) The ovary showing numerous mature follicles. (b) The PCNA expression in ovary is remarkably increased by immunohistochemistry (IHC). (c-d) POI ovary. (c) The Atretic follicles (arrowhead; ATF) are highly increased in POI ovary. (d) The PCNA expression in ovary is extremely decreased by IHC. Interestingly, PCNA expression is not detected in antral follicle of POI ovary. (Low magnification: ×15, High magnification: ×100). Primordial follicle (PrF), Primary follicle (PF), Secondary follicle (SF), Antral follicle (AF), Corpus luteum (CL), Follicular antrum (FA), Egg (E), Atretic follicle (ATF) and Surface epithelium (EP)

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