Table 2 Clinical study of stem cell therapy on POF
Status | Phase | Stem cell type | Sponsor | Clinical Trial Number |
|---|---|---|---|---|
Completed | 1,2 | OCT4 marker measured | Al-Azhar University | NCT02151890 |
hUCMSC and hCBMNC transplantation | Shenzhen Beike Bio-Technology Co., Ltd | NCT01742533 | ||
autologous MSCs injection | El-Rayadh Fertility Centre | NCT02043743 | ||
autologous MSCs treatment + OCT4 marker measured | Sayed Bakry | NCT02062931 | ||
Recruiting | – | BMSC treatment directly to ovary | University of Illinois at Chicago | NCT02696889 |
1 | embryonic stem cell derived MSC-like cell transplantation directly into bilateral ovaries | Chinese Academy of Sciences | NCT03877471 | |
1,2 | VSELs from the patient’s peripheral bloodinjected in bilateral oviducts + hormone and menstrual conditions measured | Fuda Cancer Hospital, Guangzhou | NCT03985462 | |
– | Derivation of hESC lines | Hadassah Medical Organization | NCT00353197 | |
Active | 2 | hUCMSC treatment | Sclnow Biotechnology Co., Ltd. | NCT03816852 |
1,2 | intraovarian transplantation of autologous BMSCs & MSCs. | Stem Cells Arabia | NCT03069209 |