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Table 2 Univariate survival analyses for the patients with SSC of ovary in the SEER database (2004–2016, N = 180)

From: Poorer prognosis of ovarian squamous cell carcinoma than serous carcinoma: a propensity score matching analysis based on the SEER database

  Overall survival Cause-specific survival
Variables HR 95%CI P-value HR 95%CI P-value
Age
 ≤67 1    1   
 > 67 2.24 1.48–3.38 < 0.001 1.91 1.16–3.14 0.011
Race
 White 1    1   
 Black 1.08 0.60–1.94 0.798 0.85 0.39–1.86 0.677
 Others 0.86 0.48–1.62 0.638 0.96 0.47–1.94 0.901
Tumor size (mm)
 < 50 1    1   
 50–150 1.99 1.05–3.75 0.034 2.23 0.99–5.07 0.054
 > 150 1.75 0.82–3.74 0.150 2.12 0.84–5.32 0.110
Laterality
 Unilateral 1    1   
 Bilateral 2.83 1.37–5.85 0.005 3.33 1.44–7.70 0.005
Serum CA125
 Negative 1    1   
 Positive 1.42 0.78–2.57 0.248 1.82 0.86–3.83 0.116
FIGO stage
 I 1    1   
 II 2.62 1.43–4.79 0.002 4.06 1.93–8.54 < 0.001
 III 2.99 1.66–5.36 < 0.001 3.30 1.54–7.06 0.002
 IV 9.56 5.27–17.36 < 0.001 16.52 7.86–34.72 < 0.001
Grade
 G1/G2 1      
 G3/G4 1.23 0.78–1.92 0.371 1.18 0.70–2.02 0.533
SEER stage
 Localized 1    1   
 Regional 2.62 1.37–5.03 0.004 4.27 1.77–10.33 0.001
 Distant 6.40 3.38–12.1 < 0.001 9.70 4.06–23.15 < 0.001
Lymphadenectomy
 Yes 1    1   
 No 1.67 1.11–2.50 0.014 1.70 1.04–2.78 0.034
Radiotherapy
 Yes 1    1   
 No 0.76 0.47–1.22 0.254 0.57 0.33–0.98 0.041
Chemotherapy
 Yes 1    1   
 No 1.01 0.68–1.49 0.964 1.21 0.75–1.94 0.437
Surgery
 Yes 1      
 No 2.80 1.49–5.25 0.001 3.14 1.36–7.27 0.007
  1. Abbreviations: SCC Squamous cell carcinoma; SEER Surveillance Epidemiology and End Results Program; FIGO International Federation of Gynecology and Obstetrics