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Table 2 Association between MMP protein expression and steroid hormone receptor in epithelium of the tumors by histological subtype

From: Expression of metalloproteinases MMP-2 and MMP-9 is associated to the presence of androgen receptor in epithelial ovarian tumors

 

n

AR

ERα

PR

+

-

P

+

-

P

+

-

P

MMP-2

 SBT

20

12/14

5/6

1.0

10/12

7/8

1.0

14/14

3/6

0.018

 HGSC

21

13/13

5/8

0.042

5/6

13/15

1.0

10/11

8/10

0.586

 Endometrioid

21

10/12

6/9

0.611

10/12

6/9

0.611

10/13

6/8

1.0

 Mucinous

11

7/7

3/4

0.364

2/2

8/9

1.0

3/3

7/8

1.0

 LGSC

9

7/7

1/2

0.222

4/5

4/4

1.0

6/7

2/2

1.0

MMP-9

 SBT

19

9/13

2/6

0.319

7/12

4/7

1.0

7/14

4/5

0.338

 HGSC

21

8/13

5/8

1.0

4/6

9/15

1.0

7/11

6/10

1.0

 Endometrioid

21

9/12

2/9

0.030

8/12

3/9

0.198

7/13

4/8

1.0

 Mucinous

11

4/7

1/4

0.545

0/2

5/9

0.455

1/3

4/8

1.0

 LGSC

9

4/7

1/2

1.0

1/5

4/4

0.048

1/2

4/7

1.0

  1. SBT serous borderline tumor, HGSC high grade serous carcinoma, LGSC low grade serous carcinoma
  2. P values obtained by Fisher’s exact test