Table 4 Hazard ratio for metalloproteinases, sexual hormone receptors, and clinical characteristic in epithelial ovarian tumors
Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
Factor | HR | 95% CI | p | HR | 95% CI | p |
MMP-2 epithelium | 10.8 | 1.36–25.7 | 0.02 | 11.5 | 1.42–92.7 | 0.02 |
MMP-2 stroma | 0.15 | 0.05–0.42 | <0.001 | 0.16 | 0.05–0.50 | 0.002 |
MMP-9 epithelium | 1.49 | 0.534.19 | 0.44 | 0.79 | 0.18–3.35 | 0.75 |
MMP-9 stroma | 0.52 | 0.11–2.33 | 0.38 | 2.97 | 0.39–22.5 | 0.29 |
Androgen receptor | 1.85 | 0.68–5.04 | 0.23 | 4.03 | 0.54–30.4 | 0.18 |
Estrogen receptor α | 0.65 | 027–1.57 | 0.34 | 1.52 | 0.48–4.86 | 0.48 |
Progesterone receptor | 0.95 | 0.40–2.37 | 0.95 | 1.41 | 0.36–5.82 | 0.61 |
FIGO stage | 3.88 | 2.14–7.16 | <0.001 | 12.4 | 1.57–97.7 | 0.02 |
Age at diagnosis | 1.02 | 0.99–1.05 | 0.18 | 1.05 | 1.10–1.11 | 0.03 |
Histological subtype | 3.15 | 0.73–13.7 | 0.13 |