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Table 4 Hazard ratio for metalloproteinases, sexual hormone receptors, and clinical characteristic in epithelial ovarian tumors

From: Expression of metalloproteinases MMP-2 and MMP-9 is associated to the presence of androgen receptor in epithelial ovarian tumors

   Univariate    Multivariate  
Factor HR 95% CI p HR 95% CI p
MMP-2 epithelium 10.8 1.36–25.7 0.02 11.5 1.42–92.7 0.02
MMP-2 stroma 0.15 0.05–0.42 <0.001 0.16 0.05–0.50 0.002
MMP-9 epithelium 1.49 0.534.19 0.44 0.79 0.18–3.35 0.75
MMP-9 stroma 0.52 0.11–2.33 0.38 2.97 0.39–22.5 0.29
Androgen receptor 1.85 0.68–5.04 0.23 4.03 0.54–30.4 0.18
Estrogen receptor α 0.65 027–1.57 0.34 1.52 0.48–4.86 0.48
Progesterone receptor 0.95 0.40–2.37 0.95 1.41 0.36–5.82 0.61
FIGO stage 3.88 2.14–7.16 <0.001 12.4 1.57–97.7 0.02
Age at diagnosis 1.02 0.99–1.05 0.18 1.05 1.10–1.11 0.03
Histological subtype     3.15 0.73–13.7 0.13
  1. HR Hazard ratio, CI confidence interval