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Table 2 Univariate and multivariate analysis of factors associated with disease-free survival and overall survival rates of ovarian cancer following surgical resection

From: Cul4B promotes the progression of ovarian cancer by upregulating the expression of CDK2 and CyclinD1

  Disease-free survival Overall survival
Clinicopathological factors Univariate P Multivariate Univariate P Multivariate
Hazard ratio 95% CI p Hazard ratio 95% CI p
Age < 50 vs ≥50 0.034     0.049    
Non-serous tumour vs Serous tumour 0.279     0.386    
Grade 1 vs Grade 2–3 0.042 2.485 0.994–6.211 0.052 0.032 2.798 1.116–7.013 0.028
Tumor size < 10 cm vs ≥10 cm 0.244     0.212    
FIGO I-II vs III-IV 0.028     0.016 1.718 1.018–2.900 0.043
CA125 < 70 U/L vs ≥70 U/L 0.544     0.642    
Intratumoral Cul4B expression 0.000 3.797 2.142–6.733 0.000 0.000 3.240 1.844–5.692 0.000