From: Cul4B promotes the progression of ovarian cancer by upregulating the expression of CDK2 and CyclinD1
 | Disease-free survival | Overall survival | ||||||
---|---|---|---|---|---|---|---|---|
Clinicopathological factors | Univariate P | Multivariate | Univariate P | Multivariate | ||||
Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p | |||
Age < 50 vs ≥50 | 0.034 |  |  |  | 0.049 |  |  |  |
Non-serous tumour vs Serous tumour | 0.279 | Â | Â | Â | 0.386 | Â | Â | Â |
Grade 1 vs Grade 2–3 | 0.042 | 2.485 | 0.994–6.211 | 0.052 | 0.032 | 2.798 | 1.116–7.013 | 0.028 |
Tumor size < 10 cm vs ≥10 cm | 0.244 |  |  |  | 0.212 |  |  |  |
FIGO I-II vs III-IV | 0.028 |  |  |  | 0.016 | 1.718 | 1.018–2.900 | 0.043 |
CA125 < 70 U/L vs ≥70 U/L | 0.544 |  |  |  | 0.642 |  |  |  |
Intratumoral Cul4B expression | 0.000 | 3.797 | 2.142–6.733 | 0.000 | 0.000 | 3.240 | 1.844–5.692 | 0.000 |