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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Anti-proliferative activities of Byrsocarpus coccineus Schum. and Thonn. (Connaraceae) using ovarian cancer cell lines

Fig. 4

Effect of B. coccineus ethanol leaf extract on apoptosis of ovarian cancer cells. OvCa cells were treated with different dosage of B. coccineus extract (OVCAR-3: 446.5 μg/mL; and SW 626: 486.94 μg/mL) for 48 h, and apoptosis was assessed by staining with Annexin V-(conjugated with FITC)/ PI followed by flow cytometry. Quadrant Q1, Q2, Q3 and Q4 represents the percentages of necrotic (Annexin (−)/(PI (+), late (Annexin (+)/(PI (+), early (Annexin (+)/(PI (−) apoptotic, and viable (Annexin (−)/(PI (−) cells, respectively. DMSO was used in untreated cells. Upon treatment with extract, both cell lines showed higher number of apoptotic cells in early apoptotic phase compared to in untreated cells

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