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Table 1 Relationship between clinicopathological parameters and different levels of plasma D-dimer, fibrinogen and serum CA125 in 104 patients with recurrent EOC

From: Platelet count as a biomarker for monitoring treatment response and disease recurrence in recurrent epithelial ovarian cancer

  

Platelet count

1000cells/μl

Plasma Fibrinogen

g/l

Plasma D-dimer

mg/l

serum CA125

U/ml

Variable

n

≤300

> 300

P

2–4

> 4

P

≤0.3

> 0.3

P

≤35

> 35

P

Age, y

   

0.340

  

0.386

  

0.566

  

0.685

 ≤ 55

39

28

21

 

27

12

 

5

34

 

1

38

 

 > 55

65

26

39

 

48

17

 

9

56

 

2

63

 

Stage

   

0.335

  

0.473

  

0.373

  

0.531

 I or and II

23

11

12

 

16

7

 

4

19

 

1

22

 

 III or and IV

81

33

48

 

59

22

 

10

71

 

2

79

 

Histological type

   

0.432

  

0.016

  

0.402

  

0.324

 Serous

64

28

36

 

41

23

 

6

58

 

1

63

 

 Non serous

40

16

24

 

34

6

 

8

32

 

2

38

 

Grade

   

0.021

  

0.273

  

0.410

  

0.549

 Low

24

15

9

 

19

5

 

4

20

 

1

23

 

 High

80

29

51

 

56

24

 

10

70

 

2

78

 

Postoperative residual disease

   

0.069

  

0.514

  

0.402

  

0.301

 Microscopic

66

32

34

 

48

18

 

8

58

 

1

65

 

 Macroscopic

38

12

26

 

27

11

 

6

32

 

2

36

 
  1. CI confidence interval, HR hazard ratio