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Table 1 Relationship between clinicopathological parameters and different levels of plasma D-dimer, fibrinogen and serum CA125 in 104 patients with recurrent EOC

From: Platelet count as a biomarker for monitoring treatment response and disease recurrence in recurrent epithelial ovarian cancer

   Platelet count
1000cells/μl
Plasma Fibrinogen
g/l
Plasma D-dimer
mg/l
serum CA125
U/ml
Variable n ≤300 > 300 P 2–4 > 4 P ≤0.3 > 0.3 P ≤35 > 35 P
Age, y     0.340    0.386    0.566    0.685
 ≤ 55 39 28 21   27 12   5 34   1 38  
 > 55 65 26 39   48 17   9 56   2 63  
Stage     0.335    0.473    0.373    0.531
 I or and II 23 11 12   16 7   4 19   1 22  
 III or and IV 81 33 48   59 22   10 71   2 79  
Histological type     0.432    0.016    0.402    0.324
 Serous 64 28 36   41 23   6 58   1 63  
 Non serous 40 16 24   34 6   8 32   2 38  
Grade     0.021    0.273    0.410    0.549
 Low 24 15 9   19 5   4 20   1 23  
 High 80 29 51   56 24   10 70   2 78  
Postoperative residual disease     0.069    0.514    0.402    0.301
 Microscopic 66 32 34   48 18   8 58   1 65  
 Macroscopic 38 12 26   27 11   6 32   2 36  
  1. CI confidence interval, HR hazard ratio