Skip to main content

Table 2 Univariate and multivariate analysis of prognostic factors in progression free survival

From: Platelet count as a biomarker for monitoring treatment response and disease recurrence in recurrent epithelial ovarian cancer

  Univariate analysis Multivariate analysis
Variable HR 95.0% CI P value HR 95.0% CI P value
Age (y)
≤55 vs. > 55
1.351 0.903 −2.020 0.143
Postoperative residual disease
Microscopic vs. Macroscopic
3.637 2.376 −5.566 P < 0.001 2.761 1.752 −4.351 P < 0.001
Grade
Low vs. High
2.499 1.535 −4.067 P < 0.001 1.912 1.141 −3.202 0.014
Stage
I or II vs. III or IV
2.344 1.360 −4.039 0.002 1.592 0.883 −2.872 0.122
Platelet count (1000/μl)
≤300 vs. > 300
1.820 1.214 −2.728 0.004 1.626 1.073 −2.466 0.022
Platelet count reduction
> 25% vs. ≤25%
1.594 1.068 −2.378 0.023 1.651 1.100 −2.478 0.015
Plasma fibrinogen(g/l)
2–4 vs. > 4
0.914 0.592 − 1.411 0.685  
Plasma D-dimer (mg/l)
≤0.3 vs. > 0.3
0.894 0.507 −1.574 0.697
  1. CI confidence interval, HR hazard ratio