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Table 1 Patient characteristics in relation to preoperative blood parameters and SIR marks

From: Serum D-dimer, albumin and systemic inflammatory response markers in ovarian clear cell carcinoma and their prognostic implications

Characteristic Na (%) CA125b (U/ml) Albumin b (g/l) Leukocyte differential counts b (k/μl) Platelet b (k/μl) D-dimer b (mg/l) Ratio b
Lymphocyte Monocyte Neutrophil NLR MLR PLR
All cases 84 187.9 (6.5–5000*) 40.7 (25.9–52.1) 1.5 (0.4–2.9) 0.4 (0.03–1.6) 4.1 (1.9–15.2) 299 (124–608) 1.66 (0.19–55.20) 2.7 (1.1–20.3) 0.28 (0.03–2.00) 193.9 (77.5–955.0)
Age (years)
  ≤ 52 42 (50) 188.0 (6.5–2854) 40.7 (33.1–49.4) 1.5 (0.6–2.9) 0.4 (0.2–1.0) 4.0 (1.9–12.2) 301 (124–500) 1.66 (0.19–55.20) 2.6 (1.1–20.3) 0.25 (0.12–0.83) 201.7 (77.5–615.0)
  > 52 42 (50) 165.0 (11.1–5000*) 40.4 (25.9–52.1) 1.5 (0.4–2.4) 0.4 (0.03–1.6) 4.4 (1.9–15.2) 296 (147–608) 1.66 (0.20–20.00) 2.8 (1.1–20.3) 0.32 (0.03–2.00) 191.0 (92.1–955.0)
P value   0.589 0.056 0.874 0.039 0.826 0.871 0.756 0.826 0.053 0.940
FIGO stage
 IC-II 47 (56.0) 70.5 (6.5–1930.0) 43.6 (29.6–52.1) 1.5 (0.9–2.9) 0.4 (0.03–1.0) 3.6 (1.9–10.7) 292 (124–500) 1.49 (0.19–55.20) 2.2 (1.1–7.1) 0.21 (0.03–0.67) 167.5 (77.5–500.0)
 III-IV 37 (44.0) 276.9 (45.6–5000*) 39.2 (25.9–49.2) 1.4 (0.4–2.4) 0.4 (0.3–1.6) 4.6 (1.9–15.2) 311 (147–608) 2.61 (0.69–11.03) 3.2 (1.1–20.3) 0.33 (0.18–2.00) 230.0 (101.7–955.0)
P value   < 0.001 < 0.001 0.031 0.002 0.009 0.320 0.001 0.001 < 0.001 0.006
Residual tumor (cm)
 0 63 (75.0) 157.4 (6.5–5000*) 41.7 (28.3–52.1) 1.5 (0.6–2.9) 0.4 (0.03–1.6) 3.8 (1.9–15.2) 292 (124–608) 1.66 (0.19–55.20) 2.4 (1.1–7.1) 0.25 (0.03–0.70) 173.5 (77.5–500)
  ≤ 1 14 (16.7) 371.4 (45.6–1845.3) 38.4 (29.0–43.7) 1.4 (0.9–2.4) 0.5 (0.3–0.9) 4.7 (2.7–6.6) 318 (202–593) 2.53 (0.69–9.30) 3.2 (1.3–5.7) 0.35 (0.19–0.82) 219.8 (107.1–539.1)
  > 1 7 (8.3) 475.1 (151.6–1866.0) 33.2 (25.9–49.2) 0.9 (0.4–1.8) 0.6 (0.3–1.4) 8.1 (2.7–12.2) 342 (253–382) 3.29 (0.75–6.06) 8.2 (2.8–20.3) 0.67 (0.39–2.00) 383.3 (190.0–955.0)
P value   0.007 0.006 0.008 0.002 0.005 0.314 0.064 < 0.001 < 0.001 0.004
Platinum response
 Sensitive 58 (69.0) 124.6 (6.47–5000*) 41.7 (29.0–52.1) 1.5 (0.6–2.9) 0.4 (0.03–1.0) 3.8 (1.9–10.7) 279 (124–500) 1.66 (0.19–20.00) 2.4 (1.1–7.1) 0.25 (0.03–0.70) 176.7 (77.5–500.0)
 resistant 24 (28.6) 294.3 (38.21–1866.0) 39.2 (25.9–49.2) 1.5 (0.4–2.4) 0.5 (0.2–1.6) 4.9 (2.1–15.2) 316 (202–608) 3.82 (0.44–55.20) 3.2 (1.1–20.3) 0.35 (0.15–2.00) 214.3 (126.3–955.0)
P value   0.002 0.012 0.400 0.011 0.003 0.157 < 0.001 0.002 0.004 0.060
  1. Abbreviations: SIR systemic inflammatory response, NLR neutrophil to lymphocyte ratio, MLR monocyte to lymphocyte ratio, PLR platelet to lymphocyte ratio
  2. P values with statistical significance were denoted
  3. a Categorical data are shown in absolute value and proportion
  4. b Continuous variables are represented by median and range
  5. * The upper limit of CA125 detection is 5000