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Table 2 Predictive values of preoperative blood parameters and NLR, MLR for determination of platinum resistance

From: Serum D-dimer, albumin and systemic inflammatory response markers in ovarian clear cell carcinoma and their prognostic implications

Variables AUC P 95% CI Cut-off value Se% Sp% PPV% NPV%
MLR 0.701 0.004 0.577–0.825 0.3 62.5 70.7 46.9 82.0
NLR 0.710 0.003 0.589–0.832 2.28 87.5 48.3 41.2 90.3
ALB 0.676 0.013 0.547–0.804 39.6 58.3 74.1 81.1 48.3
CA125 0.713 0.003 0.601–0.825 135.15 91.7 51.7 44.0 93.8
D2 0.761 < 0.001 0.646–0.876 3.27 58.3 84.5 60.9 83.1
  1. Abbreviations: MLR monocyte to lymphocyte ratio, NLR neutrophil to lymphocyte ratio, ALB albumin, CA125 carbohydrate antigen 125, D2 D-dimer, AUC area under the curve, CI confidence interval, Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value
  2. P values with statistical significance were denoted