Serum D-dimer, albumin and systemic inflammatory response markers in ovarian clear cell carcinoma and their prognostic implications

Table 2 Predictive values of preoperative blood parameters and NLR, MLR for determination of platinum resistance

Variables	AUC	P	95% CI	Cut-off value	Se%	Sp%	PPV%	NPV%
MLR	0.701	0.004	0.577–0.825	0.3	62.5	70.7	46.9	82.0
NLR	0.710	0.003	0.589–0.832	2.28	87.5	48.3	41.2	90.3
ALB	0.676	0.013	0.547–0.804	39.6	58.3	74.1	81.1	48.3
CA125	0.713	0.003	0.601–0.825	135.15	91.7	51.7	44.0	93.8
D2	0.761	< 0.001	0.646–0.876	3.27	58.3	84.5	60.9	83.1

Abbreviations: MLR monocyte to lymphocyte ratio, NLR neutrophil to lymphocyte ratio, ALB albumin, CA125 carbohydrate antigen 125, D2 D-dimer, AUC area under the curve, CI confidence interval, Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value
P values with statistical significance were denoted

ISSN: 1757-2215