Serum D-dimer, albumin and systemic inflammatory response markers in ovarian clear cell carcinoma and their prognostic implications

Table 4 Summary of studies examining SIR as prognostic factors in OCCC patients

	Kim 2016 [19]	Zhang 2017 [20]	Kwon 2018 [12]	Yoshida 2019 [13]	The present study
Sample size	109	155	109	83	84
Advanced-stage %	37.5	29	41.3	0	44
platinum resistance %	18.3	12.9	22	NA	28.6
Prognostic factor for PFS	NLR, PLR	NLR	None	None	None
Prognostic factor for OS	None	NLR	LMR	NLR	None
Cut-off value	4.44 for resistance 2.8 for survival	NA	NA	3.26 for OS	2.28 for resistance

Abbreviations: SIR Systemic inflammatory response, NLR neutrophil to lymphocyte ratio, PLR platelet to lymphocyte ratio, LMR lymphocyte to monocyte ratio, PFS progression-free survival, OS overall survival, NA not available

ISSN: 1757-2215