Fig. 6

miR-27b-5p inhibits tumor growth of SKOV3 cell in vivo. A. miR-NC or miR-27b-5p stable transfected SKOV3 cells were injected into nude mice. Mice were sacrificed at 35 days post-injection. B. Overexpressed miR-27b-5p suppressed tumor growth. C. Analysis of tumor weight after xenograft tumor removed. D. The level of miR-27b-5p in tumor tissue was detected using qRT-PCR assay. E. IHC staining for CXCL1 in xenograft tumor and CXCL1 positive staining was shown using histogram. ^**P < 0.05 vs. miR-NC