Fig. 1

Troxerutin reduced body weight, improved abnormal ovarian morphology and function in PCOS rats. a Body weight b Hematoxylin and eosin staining of representative ovaries (c) Percentage of the number of follicles of total d Representative vagina smear and estrus cycle. For a and c, P values were determined by one-way ANOVA with Tukey’s multiple comparison test and data were presented as means±s.e.m. n = 12 rats per group. *P < 0.05, **P < 0.01, ***P < 0.001 vs. sham group; ^#P < 0.05, ^##P < 0.01 vs. PCOS group. For b, follicles in various stages of development were indicated by black triangles, corpora lutea were indicated by asterisks, while the cystic follicles were indicated by hashtags. Scale bar: 200 μm. For d, P,proestrus; E,estrus;M,metestrus;D,diestrus.Scale bar: 50 μm. Images were representative of three independent experiments with similar results