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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: miRNA expression profile changes in the peripheral blood of monozygotic discordant twins for epithelial ovarian carcinoma: potential new biomarkers for early diagnosis and prognosis of ovarian carcinoma

Fig. 2

Hierarchical cluster analysis of the expression of 99 miRNAs. Legend: BR 2028: Healthy Brother, BRCA1 negative (non-BRCA1 mutation carrier); BR 1861: Healthy Niece, BRCA1 positive (BRCA1 mutation carrier); BR 1860: Healthy Daughter, BRCA1 negative; BR 1447: Healthy Monozygotic twin, BRCA1 positive; BR 1639: Monozygotic twin diagnosed with ovarian cancer, BRCA1 positive; BR 2030: Healthy Sister, BRCA1 positive; BR 1546: Healthy Sister, BRCA1 positive; BR 1547: Healthy Sister, BRCA1 positive. The miRNAs that may be effective in the etiology of ovarian cancer were identified after the comparison of monozygotic twins who were phenotypically discordant for ovarian cancer diagnosis in group 1

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