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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: microRNA-1271-5p/TIAM1 suppresses the progression of ovarian cancer through inactivating Notch signaling pathway

Fig. 4

miR-1271-5p inhibited the development of OC through downregulating TIAM1. a-b The cell viability of OVCAR-3 and SK-OV-3 cells was detected by CCK-8 analysis, **P < 0.01 versus NC group, ##P < 0.01 versus inhibitor or mimic group, &&P < 0.01 versus si-TIAM1 or TIAM1 group. c-d A colony formation test was conducted to explore the clongenic ability of OVCAR-3 and SK-OV-3 cells. The number of colonies was counted, **P < 0.01 versus NC group, ##P < 0.01 versus inhibitor or mimic group, &&P < 0.01 versus si-TIAM1 or TIAM1 group. e-f Transwell migration and invasion experiments were used to investigate the migration and invasion capabilities of OVCAR-3 and SK-OV-3 cells, **P < 0.01 versus NC group, ##P < 0.01 versus inhibitor or mimic group, &&P < 0.01 versus si-TIAM1 or TIAM1 group

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