Skip to main content
Fig. 7 | Journal of Ovarian Research

Fig. 7

From: Long non-coding RNA PTPRG-AS1 promotes cell tumorigenicity in epithelial ovarian cancer by decoying microRNA-545-3p and consequently enhancing HDAC4 expression

Fig. 7

The role of the PTPRG-AS1/miR-545-3p/HDAC4 pathway in EOC cell growth in vivo. a Representative images of subcutaneous tumors after injection with CAOV-3 cells transduced with lentivirus carrying sh-PTPRG-AS1 or sh-NC. b The growth curves of subcutaneous tumors after treatment with sh-PTPRG-AS1 or sh-NC. c The weight of subcutaneous tumors in sh-PTPRG-AS1 or sh-NC groups after treatment with sh-PTPRG-AS1 or sh-NC. d, e RT-qPCR measurement of the expression of PTPRG-AS1 and miR-545-3p in tumor xenografts. f The protein level of HDAC4 in tumor xenografts was determined by western blot analysis. g IHC analysis was applied to assess HDAC4 and Ki-67 expression in the tumor xenografts. **P < 0.01

Back to article page