Fig. 2

Association of KLK5 expression levels with KLK7 expression levels in advanced HGSOC. By applying the Mann-Whitney test, KLK5 mRNA expression levels were significantly correlated with KLK7 mRNA expression levels (a, p < 0.001). Similarly, a strong positive relationship was observed between KLK5 and KLK7 at the antigen level, determined by ELISA in tumor extracts (b, p < 0.001). For both, KLK7 mRNA and antigen levels, the 67th percentile (tertiles 1 + 2 versus tertile 3) was used for dichotomization into a low versus high group