Table 1 Patients’ demographics and clinicopathological characteristics
Variables | All patients n (%) | Training set n (%) | Validation set n (%) | P |
|---|---|---|---|---|
Total | 1541 (100.0) | 1079 (70.0) | 462 (30.0) | |
Age, years | 0.984 | |||
< 50 | 413 (26.8) | 290 (26.9) | 124 (26.8) | |
50–60 | 609 (39.5) | 425 (39.4) | 184 (39.8) | |
> 60 | 518 (33.6) | 364 (33.7) | 154 (33.3) | |
Tumor size, cm | 0.325 | |||
≤ 12 | 810 (52.6) | 576 (53.4) | 234 (50.6) | |
> 12 | 731 (47.4) | 503 (46.6) | 228 (49.4) | |
Race | 0.524 | |||
White | 1154 (74.9) | 813 (75.3) | 341 (73.8) | |
Other | 387 (25.1) | 266 (24.7) | 121 (26.2) | |
Laterality | 0.289 | |||
Unilateral | 1374 (89.2) | 968 (89.7) | 406 (87.9) | |
Bilateral | 167 (10.8) | 111 (10.3) | 56 (12.1) | |
AJCC Stage (7th) | 0.730 | |||
I | 979 (67.5) | 687 (63.7) | 292 (63.2) | |
II | 167 (10.8) | 111 (10.3) | 56 (12.1) | |
III | 302 (19.6) | 214 (19.8) | 88 (19.0) | |
IV | 395 (6.0) | 67 (6.2) | 26 (5.6) | |
Grade | 0.167 | |||
I/II | 121 (7.9) | 87 (8.1) | 34 (7.4) | |
III | 588 (38.2) | 429 (39.8) | 159 (34.4) | |
IV | 398 (25.8) | 266 (24.7) | 132 (28.6) | |
Unknown | 434 (28.2) | 297 (27.5) | 137 (29.7) | |
LN dissected, n | 0.154 | |||
No | 318 (20.6) | 217 (20.1) | 101 (21.9) | |
1–10 | 446 (28.9) | 328 (30.4) | 118 (25.5) | |
> 10 | 777 (50.4) | 534 (49.5) | 243 (52.6) | |
LN | 0.233 | |||
No dissection or Negative | 1370 (88.9) | 966 (89.5) | 404 (87.4) | |
Positive | 171 (11.1) | 113 (10.5) | 58 (12.6) | |
Organ Metastasis | 0.939 | |||
No | 1505 (97.7) | 1054 (97.7) | 451 (97.6) | |
Yes | 36 (2.3) | 25 (2.3) | 11 (2.4) | |
Radiotherapy | 0.312 | |||
No/Unknown | 1509 (97.9) | 1054 (97.7) | 451 (98.5) | |
Yes | 32 (2.1) | 25 (2.3) | 7 (1.5) | |
Chemotherapy | 0.800 | |||
No/Unknown | 276 (17.9) | 195 (18.1) | 81 (17.5) | |
Yes | 1265 (82.1) | 884 (81.9) | 381 (82.5) |