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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells

Fig. 4

STAT4 promotes the apoptosis of GCs. The pcDNA3.1-STAT4 decreased cell apoptosis rate (a), but the STAT4-siRNA increased cell apoptosis rate of GCs (b); The cell apoptosis was assessed by Annexin V-FITV/PI. The cells in lower right quadrant were annexin-positive/PI-negative early apoptotic cells. The cells in the upper right quadrant were annexin-positive/PI-positive late apoptotic cells. Compared to the blank group, the fold change of the percentage of cells undergoing early and late apoptosis were presented in the barplot. ** indicates P < 0.01. Data were represented as means ± SD

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