Evaluation of safety, feasibility and efficacy of intra-ovarian transplantation of autologous adipose derived mesenchymal stromal cells in idiopathic premature ovarian failure patients: non-randomized clinical trial, phase I, first in human

Table 2 Demographic and clinical characteristics of premature ovarian failure (POF) patients

No.	Age	BMI	Cell count	Ovary volume left (cc)	Ovary volume right (cc)	LH (mIU/ml)	FSH 1^a (mIU/ml)	FSH 2^a (mIU/ml)	AMH (ng/ml)	AFC	Affected ovary
1	38	27.0	5 × 10⁶	6.6	4.1	72	100.0	100.0	0.10	3	Left
2	30	24.6	5 × 10⁶	1.0	1.5	95	85.0	43.0	0.10	0	Left
3	32	22.3	5 × 10⁶	4.7	4.3	20	25.0	28.0	0.30	2	Right
4	21	21.4	10 × 10⁶	2.9	2	20	41.0	72.0	0.10	0	Right
5	35	29.6	10 × 10⁶	2.1	2	38	52.0	89.0	0.10	0	Left
6	33	21.6	10 × 10⁶	3.0	-^b	15	59.9	25.0	0.10	0	Left
7	34	26.3	15 × 10⁶	1.3	1	41	64.0	67.0	0.03	0	Right
8	35	24.8	15 × 10⁶	1.0	4	67	86.0	103.0	0.10	3	Right
9	33	21.6	15 × 10⁶	0.75	0.75	17	67.0	98.1	0.20	0	Left

BMI Body mass index, LH Luteinizing hormone, FSH Follicle-stimulating hormone, AMH AMH anti-Mullerian hormone, AFC Antral Follicle Count
^aAccording ESHRE identification FSH evaluated twice;1: Administration FSH; 2: transplantation day FSH
^bNot detected by vaginal ultrasonography

ISSN: 1757-2215