Fig. 1
From: Germline variation of Ribonuclease H2 genes in ovarian cancer patients
a. Sequencing of RNASEH2B variant p.C44X. Figure legend: Validation of RNASEH2B variant p.C44X through Sanger sequencing in a wildtype control (top) and the index ovarian cancer patient (bottom). The sense strand is shown. Heterozygosity for a T > A transversion was confirmed, changing the cysteine codon TGT to the stop codon TGA. b. Progression-free survival of ovarian cancer patients in relation to RNASEH2B levels. Figure legend: Progression-free survival of ovarian cancer patients in the TCGA database for patients with high versus low RNA levels of RNASEH2B. The Affymetrix probe 229210_at specific for RNASEH2B was used, and patients were stratified using auto-select best cut-off in KMplotter (http://kmplot.com/analysis/index.php?p=service&cancer=ovar) [11]