Fig. 2

Establishment of the PCOS model. a Changes in the active testosterone expression in mice after an effective dose of DHEA stimulation; b significant differences in the body weight between the control and model groups; c ovarian tissue sections were prepared from control or model mice for H&E staining. Antral follicle (AF), preovulatory follicle (PF), cystic follicle (CF), granulosa cell (GC), and corpora lutea (CL) were annotated. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, ^****p < 0.0001 versus untreated control mice. Data are indicated as mean ± SD (n = 3)