Age-related decline in the expression of GDF9 and BMP15 genes in follicle fluid and granulosa cells derived from poor ovarian responders

Table 2 Baseline characteristics of the patients

	group A (n = 63)	Group B (n = 65)	Group C (n = 68)
Age (years) ^abc	30.65 ± 2.57	37.37 ± 1.53	42.59 ± 1.70
Abnormal menstrual cycle	34.92% (22/63)	36.92% (24/65)	35.29% (24/68)
Duration of infertility (years) ^b	3.32 ± 2.21	4.03 ± 3.05	4.68 ± 3.00
BMI (kg/m²)	22.08 ± 2.62	22.21 ± 2.00	22.44 ± 2.62
AFC	4.05 ± 1.43	3.91 ± 1.69	3.94 ± 1.68
FSH/LH ratio	2.68 ± 1.29	2.76 ± 1.71	2.99 ± 1.21
E₂ (pg/ml)	76.12 ± 34.71	77.49 ± 52.67	85.08 ± 50.88
P (ng/ml)	0.77 ± 0.35	0.78 ± 0.33	0.84 ± 0.52
TT (ng/ml)	0.37 ± 0.15	0.36 ± 0.15	0.39 ± 0.10
AMH (ng/ml)	0.80 ± 0.39	0.78 ± 0.24	0.73 ± 0.39
PRL (ng/ml)	199.84 ± 39.35	205.58 ± 58.49	197.26 ± 59.45

Data are presented as mean ± SD or percentage (number). Abbreviations: BMI Body mass index, AFC Antral follicle count, FSH Follicle stimulating hormone, LH Luteinizing hormone, E₂ Estradiol, P Progesterone, TT Total testosterone, AMH Anti-Müllerian hormone, PRL Prolactin. The rate of abnormal menstrual cycle was compared with Chi-square test. P < 0.05 was considered as statistically significant
^a P < 0.05, group A vs. group B
^b P < 0.05, group A vs. group C
^c P < 0.05, group B vs. group C

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