From: A flexible short protocol in women with poor ovarian response over 40 years old
Parameters | FSP (Flexible short protocol) | RSP (routine short protocol) | MSP (mild stimulation protocol) | P1 | P2 | P3 | ||||
---|---|---|---|---|---|---|---|---|---|---|
Number of retrieved oocytes | 2.19 ± 1.95 | 3.53 ± 2.00 | 2.13 ± 1.81 | 0.000 | 0.743 | 0.000 | ||||
2PN rate | 76.48 ± 31.80 | 73.94 ± 31.44 | 66.29 ± 38.62 | 0.590 | 0.006 | 0.021 | ||||
Number of high- quality embryos | 1.25 ± 1.23 | 1.58 ± 1.30 | 0.99 ± 1.22 | 0.054 | 0.061 | 0.004 | ||||
Rate of high-quality embryo (%) | 62.84 ± 42.48 | 56.12 ± 41.90 | 50.71 ± 44.05 | 0.283 | 0.011 | 0.039 | ||||
Cycles with transferable embryos | 187 | 68 | 144 | NA | NA | NA | ||||
Embryo transfer cycles | 148 | 57 | 106 | NA | NA | NA | ||||
Fresh embryo transfer cycles | 22.97% (34/148) | 26.32% (15/57) | 16.04% (17/106) | 0.615 | 0.174 | 0.239 | ||||
Frozen embryo transfer cycles | 77.03% (114/148) | 73.68% (42/57) | 83.96% (89/106) | 0.615 | 0.174 | 0.239 | ||||
Mean of embryos Transferred | 1.72 | 1.81 | 1.71 | NA | NA | NA | ||||
Clinical pregnancy rate (%) | 21.62 (32/148) | 14.04 (8/57) | 8.49 (9/106) | 0.219 | 0.005 | 0.017 | ||||
Cumulative pregnancy rate (%) | 25.81 (32/124) | 17.78 (8/45) | 9.28 (9/97) | 0.278 | 0.002 | 0.007 | ||||
Implantation rate (%) | 13.33 (34/255) | 8.74 (9/103) | 5.52 (10/181) | 0.226 | 0.008 | 0.024 | ||||
Miscarriage rate (%) | 46.88 (15/32) | 37.50 (3/8) | 44.44 (4/9) | 0.634 | 0.897 | 0.892 | ||||
Live birth rate (%) | 11.49 (17/148) | 8.77 (5/57) | 4.72 (5/106) | 0.574 | 0.059 | 0.168 |