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Table 3 Laboratory outcomes of the FSP, short protocol and mild protocol

From: A flexible short protocol in women with poor ovarian response over 40 years old

Parameters FSP (Flexible short protocol) RSP (routine short protocol) MSP (mild stimulation protocol) P1   P2   P3
Number of
retrieved oocytes
2.19 ± 1.95 3.53 ± 2.00 2.13 ± 1.81 0.000 0.743 0.000
2PN rate 76.48 ± 31.80 73.94 ± 31.44 66.29 ± 38.62 0.590 0.006 0.021
Number of high- quality embryos 1.25 ± 1.23 1.58 ± 1.30 0.99 ± 1.22 0.054 0.061 0.004
Rate of high-quality embryo (%) 62.84 ± 42.48 56.12 ± 41.90 50.71 ± 44.05 0.283 0.011 0.039
Cycles with transferable embryos 187 68 144 NA NA NA
Embryo transfer cycles 148 57 106 NA NA NA
Fresh embryo transfer cycles 22.97% (34/148) 26.32% (15/57) 16.04% (17/106) 0.615 0.174 0.239
Frozen embryo transfer cycles 77.03% (114/148) 73.68% (42/57) 83.96% (89/106) 0.615 0.174 0.239
Mean of embryos
Transferred
1.72 1.81 1.71 NA NA NA
Clinical pregnancy rate (%) 21.62 (32/148) 14.04 (8/57) 8.49 (9/106) 0.219 0.005 0.017
Cumulative pregnancy rate (%) 25.81 (32/124) 17.78 (8/45) 9.28 (9/97) 0.278 0.002 0.007
Implantation rate (%) 13.33 (34/255) 8.74 (9/103) 5.52 (10/181) 0.226 0.008 0.024
Miscarriage rate (%) 46.88 (15/32) 37.50 (3/8) 44.44 (4/9) 0.634 0.897 0.892
Live birth rate (%) 11.49 (17/148) 8.77 (5/57) 4.72 (5/106) 0.574 0.059 0.168
  1. FSP flexible short protocol, NA not available
  2. P1: comparisons between FLP and routine short protocol groups
  3. P2: comparisons between FLP and mild stimulation groups
  4. P3: comparisons between the three groups
  5. Clinical pregnancy rate: number of clinical pregnancies divided by the number of embryo transfer cycles. Cumulative pregnancy rate: number of clinical pregnancies divided by the number of all patients. Implantation rate: number of gestational sacs divided by the number of embryos that were transferred. Miscarriage rate: number of miscarriage cycles divided by the number of clinical pregnancies. Live birth rate: number of live birth cycles divided by the number of embryo transfer cycles. Data are expressed as mean ± SD. P < 0.05 significantly different from control group