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Table 3 Laboratory outcomes of the FSP, short protocol and mild protocol

From: A flexible short protocol in women with poor ovarian response over 40 years old

Parameters

FSP (Flexible short protocol)

RSP (routine short protocol)

MSP (mild stimulation protocol)

P1

 

P2

 

P3

Number of

retrieved oocytes

2.19 ± 1.95

3.53 ± 2.00

2.13 ± 1.81

0.000

0.743

0.000

2PN rate

76.48 ± 31.80

73.94 ± 31.44

66.29 ± 38.62

0.590

0.006

0.021

Number of high- quality embryos

1.25 ± 1.23

1.58 ± 1.30

0.99 ± 1.22

0.054

0.061

0.004

Rate of high-quality embryo (%)

62.84 ± 42.48

56.12 ± 41.90

50.71 ± 44.05

0.283

0.011

0.039

Cycles with transferable embryos

187

68

144

NA

NA

NA

Embryo transfer cycles

148

57

106

NA

NA

NA

Fresh embryo transfer cycles

22.97% (34/148)

26.32% (15/57)

16.04% (17/106)

0.615

0.174

0.239

Frozen embryo transfer cycles

77.03% (114/148)

73.68% (42/57)

83.96% (89/106)

0.615

0.174

0.239

Mean of embryos

Transferred

1.72

1.81

1.71

NA

NA

NA

Clinical pregnancy rate (%)

21.62 (32/148)

14.04 (8/57)

8.49 (9/106)

0.219

0.005

0.017

Cumulative pregnancy rate (%)

25.81 (32/124)

17.78 (8/45)

9.28 (9/97)

0.278

0.002

0.007

Implantation rate (%)

13.33 (34/255)

8.74 (9/103)

5.52 (10/181)

0.226

0.008

0.024

Miscarriage rate (%)

46.88 (15/32)

37.50 (3/8)

44.44 (4/9)

0.634

0.897

0.892

Live birth rate (%)

11.49 (17/148)

8.77 (5/57)

4.72 (5/106)

0.574

0.059

0.168

  1. FSP flexible short protocol, NA not available
  2. P1: comparisons between FLP and routine short protocol groups
  3. P2: comparisons between FLP and mild stimulation groups
  4. P3: comparisons between the three groups
  5. Clinical pregnancy rate: number of clinical pregnancies divided by the number of embryo transfer cycles. Cumulative pregnancy rate: number of clinical pregnancies divided by the number of all patients. Implantation rate: number of gestational sacs divided by the number of embryos that were transferred. Miscarriage rate: number of miscarriage cycles divided by the number of clinical pregnancies. Live birth rate: number of live birth cycles divided by the number of embryo transfer cycles. Data are expressed as mean ± SD. P < 0.05 significantly different from control group