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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: miR-145 inhibits mitochondrial function of ovarian cancer by targeting ARL5B

Fig. 2

miR-145 inhibits mitochondrial function in ovarian cancer cells. miR-145 expression after transfection miR-145 mimic. b qRT-PCR results showed overexpression of miR-145 decreased mitochondrial DNA copy numbers. c ATP levels in overexpression of miR-145 decreased in SKOV3 and 3AO cells. d Mitochondrial membrane potential analyzed by JC-1 fluorescent probe (shown as RFP/GFP ratio) in miR-145 high-expression cells reduced. e Release of CytC was examined in both the cytosol and mitochondrial compartments. f The expression levels of mitochondrial markers (SDHA and HSP60) in upregulation of miR-145 expression cells by Western blotting. *P < 0.05, **P < 0.01

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