Fig. 2

Bubble map for GO and KEGG pathway analyses of upregulated DEGs. The top 10 items of the GO and KEGG pathway enrichment analyses are illustrated in the form of a bubble plot using the ggplot2 package for R software. A P-value < 0.05 was considered statistically significant. a biological processe, b cellular components, c molecular function, and d KEGG pathways. GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes