Skip to main content

Table 2 Diagnostic efficacy of clinicopathological parameters predicting suboptimal debulking

From: Preoperative serum levels of HE4 and CA125 predict primary optimal cytoreduction in advanced epithelial ovarian cancer: a preliminary model study

Clinical characteristics

Cutoff

Sensitivity

Specificity

PPV

NPV

Accuracy

AUC

P

Point

Age

68.5

0.16

0.98

0.83

0.66

0.67

0.57

0.281

2.00

FIGO stage

0.10

0.89

0.33

0.62

0.59

0.49

0.888

1.00

Histology

0.26

0.87

0.53

0.66

0.64

0.56

0.349

2.00

Tumor grade

0.68

0.35

0.38

0.64

0.47

0.51

0.858

1.00

Preoperative serum CA125 level(U/ml)

313.60

0.81

0.42

0.45

0.79

0.57

0.53

0.621

1.00

Preoperative serum HE4 level (pmol/L)

777.10

0.48

0.89

0.71

0.74

0.73

0.68

0.007*

2.00

ECOG performance status

0

0.23

0.87

0.50

0.65

0.63

0.55

0.489

2

ASA

3

0.07

0.94

0.40

0.63

0.61

0.50

0.959

1

  1. * means P < 0.05