Fig. 1
From: Decreased ovarian function and autophagy gene methylation in aging rats
Age-dependent declines in the ovarian index and E2 secretion in rats. (a) Ovarian index (ratio of ovarian weight to body weight). (b) Secretion of E2. E2: estradiol. The ovarian index values and the serum E2 levels of 12 M and 24 M rats were significantly lower than those of 6 M rats. 6 M: 6-month-old, 12 M:12-month-old, 24 M:24-month-old. Compared with 6 M rats, **P < 0.01,***P < 0.001,****P < 0.0001; compared with 12 M rats, ##P < 0.01