Fig. 5
From: Decreased ovarian function and autophagy gene methylation in aging rats
mRNA expression levels of Dnmt1, Dnmt2, Dnmt3A and Dnmt3B in the ovaries of rats. Compared to those in 6 M rats, the expression levels of the Dnmt1 and Dnmt2 genes in 12 M and 24 M rats were significantly decreased. However, the expression levels of the Dnmt3A and Dnmt3B genes gradually increased with aging. 6 M: 6-month-old, 12 M: 12-month-old, 24 M: 24-month-old. Compared with 6 M rats, ***P < 0.001,****P < 0.0001; compared with 12 M rats, #P < 0.05, ####P < 0.0001