Table 3 Toxicity (N = 19)
Event | Grade | ||||
|---|---|---|---|---|---|
1 | 2 | 3 | 4 | Grade 3/4 (%) | |
White blood cell decrease | 12 | 2 | 0 | 0 | 0 |
Neutrophil decrease | 3 | 2 | 7 | 2 | 9 (47) |
Febrile neutropenia | – | – | 0 | 0 | 0 |
Anemia | 8 | 5 | 2 | 0 | 2 (11) |
Platelet count decrease | 3 | 1 | 1 | 0 | 1 (5) |
Grade 2/3/4 (%) | |||||
Nausea | 3 | 2 | 0 | 0 | 2 (11) |
Vomiting | 1 | 0 | 0 | 0 | 0 |
Mucositis oral | 2 | 0 | 0 | 0 | 0 |
GI perforation | 0 | 0 | 0 | 0 | 0 |
Sensory neuropathy | 3 | 1 | 0 | 0 | 1 (5) |
Motor neuropathy | 0 | 0 | 0 | 0 | 0 |
Hypertension | 7 | 2 | 1 | 0 | 3 (16) |
Protein urea | 8 | 3 | 1 | 0 | 4 (21) |
Fatigue | 3 | 0 | 0 | 0 | 0 |
AST/ALT increase | 3 | 0 | 2 | 0 | 2 (11) |
Thromboembolic event | 0 | 0 | 1 | 0 | 1 (5) |
Nasal bleeding | 0 | 1 | 0 | 0 | 1 (5) |
Interstitial pneumonia | 0 | 0 | 1 | 0 | 1 (5) |