Fig. 1
From: Lnc-GULP1–2:1 affects granulosa cell proliferation by regulating COL3A1 expression and localization
The localization and expression of lnc-GULP1–2:1 in granulosa cells. In situ hybridization was used to detect the expression of lnc-GULP1–2:1 in human primary granulosa cells (a). Red signal, lnc-GULP1–2:1 expression. Blue signal, DAPI signal indicates nuclear localization. The yellow arrow in the merge graph shows the punctate expression of lnc-GULP1–2:1 signal in the nucleus. Bar = 50 μm. The expression of lnc-GULP1–2:1 in granulosa cells derived from normal, DOR and PCOS patient were analyzed by using real-time PCR (b & c). The GAPDH gene was used as an internal reference. DOR, diminished ovarian reserve. PCOS, polycystic ovary syndrome. p < 0.05 indicates the significant difference