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Table 3 The results of immunohistochemistry staining for ovarian mucinous carcinoma

From: Survival and biomarker analysis for ovarian mucinous carcinoma according to invasive patterns: retrospective analysis and review literature

  

Ovarian mucinous carcinoma

with infiltrative invasion

Ovarian mucinous carcinoma

with expansile invasion

p-Value

Molecule

 

n = 25

n = 24

CK7 (n (%))

Positive

24

(96.0)

24

(100.0)

0.99

Negative

1

(4.0)

0

(0.0)

 

CK20 (n (%))

Positive

11

(44.0)

15

(62.5)

0.24

Negative

14

(56.0)

9

(37.5)

 

CDX2 (n (%))

Positive

21

(84.0)

23

(95.8)

0.35

Negative

4

(16.0)

1

(4.2)

 

HER-2 (n (%))

Positive

7

(28.0)

10

(41.7)

0.38

Negative

18

(72.0)

14

(58.3)

 

CK 5/6 (n (%))

Positive

9

(36.0)

1

(4.2)

0.01

Negative

16

(64.0)

23

(95.8)

 

Androgen receptor (n (%))

Positive

2

(8.0)

0

(0.0)

0.49

Negative

23

(92.0)

24

(100.0)

 

ALDH1 (n (%))

Positive

9

(36.0)

10

(41.7)

0.77

Negative

16

(64.0)

14

(58.3)

 

CD24 (n (%))

Positive

6

(24.0)

0

(0.0)

0.02

Negative

19

(76.0)

24

(100.0)

 

CD133 (n (%))

Positive

8

(32.0)

5

(20.8)

0.52

Negative

17

(68.0)

19

(79.2)

 

PD-1 (n (%))

Positive

2

(8.0)

0

(0.0)

0.49

Negative

23

(92.0)

24

(100.0)

 

PD-L1 (n (%))

Positive

6

(24.0)

6

(25.0)

0.99

Negative

19

(76.0)

18

(75.0)

 

ZEB1 (n (%))

Positive

1

(4.0)

1

(4.2)

0.99

Negative

24

(96.0)

23

(95.8)

 

c-Met (n (%))

Positive

6

(24.0)

4

(16.7)

0.73

Negative

19

(76.0)

20

(83.3)

 

EGFR (n (%))

Positive

7

(28.0)

0

(0.0)

< 0.01

Negative

18

(72.0)

24

(100.0)

 

Snail-2 (n (%))

Positive

1

(4.0)

1

(4.2)

0.99

Negative

24

(96.0)

23

(95.8)

 
  1. Abbreviations: CK7 Cytokeratin 7, CK20 Cytokeratin 20, CDX2 Caudal type homeobox 2, HER-2 Human epidermal growth factor receptor 2, CK5/6 Cytokeratin 5/6, ALDH1 Aldehyde dehydrogenase 1, CD24 Cluster of differentiation 24, CD133 Cluster of differentiation 133, PD-1 Programmed cell death 1, PD-L1 Programmed cell death 1- ligand 1, ZEB1 Zinc finger E-box binding homeobox 1, EGFR Epithelial growth factor receptor