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Table 2 Risk factors for overall survival of PPSC patients by univariate and multivariate analyses

From: Differences between primary peritoneal serous carcinoma and advanced serous ovarian carcinoma: a study based on the SEER database

Clinical features Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age
  ≤ 49 Reference Reference
 50–69 1.70 0.99–2.92 0.056 1.66 0.96–2.85 0.069
  ≥ 70 2.71 1.57–4.67 <  0.001 2.49 1.44–4.31 0.001
Race
 White Reference    
 Black 1.20 0.75–1.90 0.445    
 others 0.84 0.59–1.18 0.317    
Marital status
 Married Reference Reference
 Not married 1.37 1.12–1.68 0.003 1.22 0.99–1.51 0.061
 Unknown 1.31 0.76–2.25 0.330 1.13 0.65–1.96 0.676
Tumor grade
 I Reference Reference
 II 3.65 1.15–11.82 0.028 5.20 1.61–16.87 0.006
 III 4.89 1.56–15.32 0.006 7.61 2.38–24.28 0.001
 IV 5.00 1.59–15.68 0.006 7.94 2.48–25.38 <  0.001
AJCC stage
 III Reference Reference
 IV 1.41 1.14–1.73 0.001 1.36 1.11–1.68 0.004
Chemotherapy
 No/Unknown Reference   Reference
 Yes 0.48 0.36–0.64 <  0.001 0.36 0.27–0.48 <  0.001
Surgery
 No/Unknown Reference Reference
 Yes 0.50 0.36–0.70 <  0.001 0.61 0.44–0.86 0.005
  1. PPSC primary peritoneal serous carcinoma, HR hazard ratio, CI confidence interval, AJCC American Joint Committee on Cancer