Clinical features | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age | ||||||
≤ 49 | Reference | – | – | Reference | – | – |
50–69 | 1.50 | 1.35–1.67 | < 0.001 | 1.38 | 1.24–1.54 | < 0.001 |
≥ 70 | 2.45 | 2.19–2.74 | < 0.001 | 1.97 | 1.75–2.21 | < 0.001 |
Race | ||||||
White | Reference | – | – | Reference | – | – |
Black | 1.20 | 1.07–1.36 | 0.002 | 1.19 | 1.05–1.34 | 0.005 |
others | 0.87 | 0.76–0.98 | 0.022 | 0.90 | 0.79–1.02 | 0.083 |
Marital status | ||||||
Married | Reference | – | – | Reference | – | – |
Not married | 1.32 | 1.24–1.41 | < 0.001 | 1.21 | 1.13–1.29 | < 0.001 |
Unknown | 1.28 | 1.08–1.52 | 0.004 | 1.12 | 0.94–1.32 | 0.205 |
Tumor grade | ||||||
I | Reference | – | – | Reference | – | – |
II | 1.87 | 1.38–2.53 | < 0.001 | 1.86 | 1.38–2.53 | < 0.001 |
III | 2.47 | 1.86–3.29 | < 0.001 | 2.29 | 1.72–3.05 | < 0.001 |
IV | 2.34 | 1.76–3.11 | < 0.001 | 2.35 | 1.77–3.13 | < 0.001 |
AJCC stage | ||||||
III | Reference | – | – | Reference | – | – |
IV | 1.63 | 1.53–1.74 | 0.001 | 1.47 | 1.37–1.57 | < 0.001 |
Chemotherapy | ||||||
No/Unknown | Reference | – | Reference | – | – | |
Yes | 0.48 | 0.44–0.52 | < 0.001 | 0.50 | 0.46–0.55 | < 0.001 |
Surgery | ||||||
No/Unknown | Reference | – | – | Reference | – | – |
Yes | 0.24 | 0.21–0.27 | < 0.001 | 0.33 | 0.29–0.37 | < 0.001 |