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Table 3 Risk factors for overall survival of ASOC patients by univariate and multivariate analyses

From: Differences between primary peritoneal serous carcinoma and advanced serous ovarian carcinoma: a study based on the SEER database

Clinical features Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age
  ≤ 49 Reference Reference
 50–69 1.50 1.35–1.67 <  0.001 1.38 1.24–1.54 <  0.001
  ≥ 70 2.45 2.19–2.74 <  0.001 1.97 1.75–2.21 <  0.001
Race
 White Reference Reference
 Black 1.20 1.07–1.36 0.002 1.19 1.05–1.34 0.005
 others 0.87 0.76–0.98 0.022 0.90 0.79–1.02 0.083
Marital status
 Married Reference Reference
 Not married 1.32 1.24–1.41 <  0.001 1.21 1.13–1.29 <  0.001
 Unknown 1.28 1.08–1.52 0.004 1.12 0.94–1.32 0.205
Tumor grade
 I Reference Reference
 II 1.87 1.38–2.53 <  0.001 1.86 1.38–2.53 <  0.001
 III 2.47 1.86–3.29 <  0.001 2.29 1.72–3.05 <  0.001
 IV 2.34 1.76–3.11 <  0.001 2.35 1.77–3.13 <  0.001
 AJCC stage
 III Reference Reference
 IV 1.63 1.53–1.74 0.001 1.47 1.37–1.57 <  0.001
Chemotherapy
 No/Unknown Reference   Reference
 Yes 0.48 0.44–0.52 <  0.001 0.50 0.46–0.55 <  0.001
Surgery
 No/Unknown Reference Reference
 Yes 0.24 0.21–0.27 <  0.001 0.33 0.29–0.37 <  0.001
  1. ASOC advanced serous ovarian cancer, HR hazard ratio, CI confidence interval, AJCC American Joint Committee on Cancer