Table 2 Risk of bias for included studies
Study | Random sequence generation | Allocation concealment | Blinding of participants and personnel | Blinding of outcome assessment | Incomplete outcome data | Selective reporting | other bias |
|---|---|---|---|---|---|---|---|
Pujade-Lauraine2010 [13] | Low risk | Low risk | High risk | Low risk | Low risk | Low risk | Low risk |
Gladieff2012 [14] | Low risk | Unclear risk | High risk | Low risk | Low risk | Low risk | Low risk |
Mahner2014 [15] | Low risk | Low risk | High risk | Low risk | Low risk | Low risk | Low risk |
Bafaloukos2010 [16] | Low risk | Low risk | Unclear risk | Low risk | Low risk | Low risk | Low risk |
Mutch2007 [17] | Low risk | Low risk | High risk | Unclear risk | Unclear risk | High risk | Low risk |
Ferrandina2008 [18] | Low risk | Low risk | High risk | Low risk | Low risk | Low risk | Low risk |
Vergote2009 [19] | Low risk | Low risk | High risk | Low risk | Low risk | Low risk | Low risk |
Colombo2012 [20] | Low risk | Low risk | High risk | Low risk | Low risk | Low risk | Low risk |
Banerjee2018 [21] | Low risk | Low risk | High risk | Low risk | Low risk | Low risk | Low risk |
Kaye2012 [22] | Low risk | Low risk | High risk | Low risk | Low risk | Low risk | Low risk |