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Table 1 Main characteristics of the selected researches

From: Comparison of the survival outcomes of laparoscopy versus laparotomy in treatment of early-stage ovarian cancer: a systematic review and meta-analysis

Study cohort Study design Year (study duration) Study region No. (LPS/LPT) Age (years) Outcome Follow up (months) BMI (kg/m2) Tumor size (cm)(LPS/LPT) Method of tumor extraction No. of tumor spillage (LPS/LPT) No. of lymph nodes removed (LPS/LPT) No. of upstaging (LPS/LPT) No. of adjuvant therapy (LPS/LPT) No. of recurrence (LPS/LPT) No. of port-site metastasis (LPS/LPT)
Lu, Q. retrospective study 2016 China 42/50 LPS:54 (14–69) OS 82 (16–152) LPS:23.5 ± 4.0 NR capsule bag NR 20/22 9/10 12/15 5/6 0
(2002–2014) LPT:58 (25–76) LPT:24.8 ± 3.2
Minig, L. retrospective comparative observational study 2016 Spain 50/58 LPS:52 (44.8–62.3) OS/PFS LPS:25.9 (11.2–38.5) LPS:23.7 (21.8–27.2) 6.75 / 10.0 endo-bag NR 15/13.5 12/8 32/34 1/7 0
(2006–2014) LPT:52 (44.8–65) LPT:34.3 (28.4–47.8) LPT:24.6 (21.8–28.5)
Gallotta, V. retrospective case-control study 2016 Italy 60/120 LPS:48 (24–73) OS/PFS 38 (24–48) NR NR NR NR 16/ 18 NR 70%, similar between LPS/LPT 5/16 0
(LPS:2007–2013;LPT:2000–2011) LPT:55 (22–81)
Ditto, A. retrospective study 2017 Italy 50/50 LPS:46.0 ± 13.4 OS/PFS LPS:49.5 ± 64 LPS:25.1 ± 3.4 NR NR NR 31/36 10/13 31/28 NR 0
(2005–2015) LPT:42.8 ± 11.2 LPT:52.6 ± 31.7 LPT:25.8 ± 5.1
Xiong, W. retrospective study 2017 China 71/31 LPS:47 ± 10 OS 50.5 LPS:23 ± 4 8/14 capsule bag NR 18.1/15.5 7/2 67/59 11/4 0
(2007–2014) LPT:49 ± 10 LPT:22 ± 3
Merlier, M. retrospective study 2000–2018 France 37/107 LPS:56.3 ± 16.8 OS/PFS LPS:24 (11–50) LPS:23.8 ± 5.0 NR NR NR 28/67 NR 34/96 2/31 0
LPT:56.2 ± 14.7 LPT:42 (22–66) LPT: 25.4 ± 5.0
  1. LPT Laparotomy, LPS Laparoscopy, BMI Body Mass Index, OS Overall Survival, PFS Progression Free Survival, NR Not Report