D5 | D6 | |||||
---|---|---|---|---|---|---|
SBT group | DBT group | P | SBT group | DBT group | P | |
Cycles (n) | 476 | 365 | 730 | 467 | ||
female age (year) | 31.80 ± 4.05 | 31.40 ± 3.78 | 0.105 | 32.92 ± 4.29 | 32.09 ± 4.20 | 0.757 |
BMI (kg/m2) | 22.01 ± 3.35 | 21.58 ± 3.46 | 0.909 | 21.83 ± 3.08 | 22.11 ± 3.24 | 0.103 |
AMH (ng/ml) | 6.07 ± 4.17 | 6.75 ± 4.30 | 0.333 | 4.82 ± 3.69 | 4.97 ± 3.96 | 0.462 |
Duration of infertility (years) | 4.78 ± 3.24 | 4.71 ± 3.04 | 0.682 | 4.86 ± 3.21 | 4.82 ± 3.20 | 0.653 |
Endometrial preparation (%) | 0.525 | 0.447 | ||||
Natural | 38.03 (181/476) | 35.89 (131/365) | 39.45 (288/730) | 37.26 (174/467) | ||
HRT | 61.97 (295/476) | 64.11 (234/365) | 60.55 (442/730) | 62.74 (293/467) | ||
Endometrial thickness (mm) | 8.97 ± 1.39 | 8.91 ± 1.42 | 0.387 | 8.95 ± 1.44 | 9.05 ± 1.46 | 0.657 |
Implantation rate | 42.44 (202/476) | 41.64 (304/730) | 0.785 | 20.82 (152/730) | 22.38 (209/934) | 0.445 |
Pregnancy rate | 42.44 (202/476) | 59.73 (218/365) | 0.000 | 20.82# (152/730) | 37.90 (177/467) | 0.000 |
Multiple pregnancy rate | 3.96 (8/202) | 39.91 (87/218) | 0.000 | 2.63 (4/152) | 19.21 (34/177) | 0.000 |
Early miscarriage rate | 22.28 (45/202) | 19.72 (43/218) | 0.521 | 27.63 (42/152) | 22.03 (39/177) | 0.240 |
Miscarriage rate | 22.77 (46/202) | 22.48 (49/218) | 0.942 | 30.92 (47/152) | 25.99 (46/177) | 0.322 |
Ectopic pregnancy rate | 0.99 (2/202) | 0.46 (1/218) | 0.947 | 0 (0/152) | 1.13 (2/177) | 0.501 |
Live birth rate | 32.35 (154/476) | 46.03 (168/365) | 0.000 | 14.25# (104/730) | 27.41 (128/467) | 0.000 |
Singleton | 31.30 (149/476) | 29.86 (109/365) | 0.654 | 14.25 (104/730) | 23.55 (110/467) | 0.000 |
Twin | 1.05 (5/476) | 16.16 (59/365) | 0.000 | 0 (0/730) | 3.85 (18/467) | 0.001 |
Preterm birth (<37weeks) | 9.74 (15/154) | 32.14 (54/168) | 0.000 | 6.67 (7/105) | 17.19 (22/128) | 0.015 |
Singleton | 8.44 (13/154) | 8.93 (15/168) | 0.877 | 6.67 (7/105) | 8.59 (11/128) | 0.584 |
Twin | 1.30 (2/154) | 23.21 (39/168) | 0.000 | 0 (0/105) | 8.59 (11/128) | 0.001 |
Gestational age (weeks) | 38.51 ± 1.75 | 36.52 ± 3.79 | 0.000 | 38.45 ± 1.58 | 37.79 ± 1.84 | 0.054 |
Singleton | 38.60 ± 1.74 | 38.37 ± 1.90 | 0.428 | 38.45 ± 1.58 | 38.29 ± 1.61 | 0.954 |
Twin | 36.33 ± 0.52 | 34.83 ± 4.28 | 0.120 | / | 36.18 ± 1.60 | / |
Birth height (mm) | 49.75 ± 1.77 | 47.82 ± 3.65 | 0.000 | 49.81 ± 1.82 | 48.97 ± 2.97 | 0.001 |
Singleton | 49.89 ± 1.65 | 49.69 ± 1.70 | 0.950 | 49.81 ± 1.82 | 49.95 ± 1.91 | 0.813 |
Twin | 46.33 ± 1.21 | 46.11 ± 4.09 | 0.197 | / | 45.55 ± 3.56 | / |
Birth weight (kg) | 3227.16 ± 459.78 | 2736.0 ± 665.34 | 0.000 | 3263.60 ± 538.74 | 3026.75 ± 599.13 | 0.101 |
Singleton | 3255.69 ± 442.21 | 3169.31 ± 468.53 | 0.944 | 3263.60 ± 538.74 | 3207.98 ± 527.65 | 0.547 |
Twin | 2523.33 ± 318.04 | 2339.42 ± 564.46 | 0.294 | / | 2445.74 ± 420.85 | / |
Low birth weight (<2500 g) | 8.18 (13/159) | 31.28 (71/227) | 0.000 | 3.85 (4/104) | 15.75 (23/146) | 0.003 |
Singleton | 5.37 (8/149) | 5.50 (6/109) | 0.962 | 3.85 (4/104) | 4.55 (5/110) | 0.999 |
Twin | 50.0 (5/10) | 55.08 (65/118) | 0.999 | / | 50.0 (18/36) | / |