Fig. 1

Alpha and beta diversity of the gut microbial communities from participants (n = 36). a: Shannon–Wiener curves, showing that the amount of sequencing data is large enough to reflect the vast majority of microbial information in the samples. b: Venn diagram, displaying the number of common and unique OTUs, and the similarity and overlap of OTUs among groups. c: Comparison of observed OUT Numbers between the three groups(P > 0.05). d: Comparisons of Chao1 indexes among the three groups(P > 0.05). e: Principal coordinate analysis (PCoA) of fecal microbiota based on weight UniFrac metric, each dot represents the bacterial community composition of one individual stool sample, and the axis titles indicates the percentage variation explained (62.52 and 9.56 % respectively). f: Dendrogram showing hierarchical cluster analysis based on weight UniFrac distance matrix to measure the closeness between individual samples