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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: Long non-coding RNA AFAP1-AS1 facilitates ovarian cancer progression by regulating the miR-107/PDK4 axis

Fig. 3

MiR-107 was the target of AFAP1-AS. a. Bioinformatics analysis predicted the binding sequences between miR-107 and AFAP1-AS1. b. Dual-luciferase reporter gene assay was utilized for verifying the binding relationship between miR-107 and AFAP1-AS1. c. RIP assay confirmed the relationship between AFAP1-AS1 and miR-107. d. qRT-PCR was performed for detecting AFAP1-AS1 expression in OC cells overexpressing AFAP1-AS1. e & f. qRT-PCR was conducted for examining miR-107 expression in cells with AFAP1-AS1 knockdown or overexpression. g & h. qRT-PCR was utilized for detecting miR-107 expression in OC tissues and cells. i. Correlation between miR-107 and AFAP1-AS1 expression levels in OC tissues. **P < 0.01 and ***P < 0.001

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Journal of Ovarian Research

ISSN: 1757-2215

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