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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Long non-coding RNA AFAP1-AS1 facilitates ovarian cancer progression by regulating the miR-107/PDK4 axis

Fig. 5

PDK4 was the target of miR-107. a. Bioinformatics analysis predicted the binding sequences between miR-107 and PDK4 3’UTR. b. Luciferase reporter gene assay was conducted for detecting the binding relationship between miR-107 and PDK4. c & d. The qRT-PCR and Western blot were used to detect the expression levels of PDK4 mRNA and protein in transfected OC cells. e & f. qRT-PCR was performed to detect PDK4 mRNA expression in OC tissues and cells. g & h. Correlation between PDK4 mRNA expression level and miR-107 expression level or AFAP1-AS1 expression level in OC tissues. **P < 0.01 and ***P < 0.001

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