Fig. 6

MiR-107 targeted PDK4 to inhibit OC cell proliferation, migration and invasion. a. MiR-107 mimic and PDK4 overexpression plasmids were co-transfected into OC cells, and CCK-8 assay was used for examining cell proliferation after transfection. b. Western blot was used to detect PCNA and cyclin D1 protein expression levels. c & d. Transwell assays were used to detect cell migration and invasion after transfection. *P < 0.05, **P < 0.01 and ***P < 0.001