Table 1 Reported cases of nongestational pure choriocarcinoma of the ovary with distant metastases at the time of diagnosis
Case | Authors (Ref) | Age | Side | Distant metastases | hCG (IU/L) | Surgery | Chemotherapy | Outcome | DNA analysis |
|---|---|---|---|---|---|---|---|---|---|
1 | Stevens et al., 1979 [21] | 19 | left | lung | 80,000-160,000 | TAH, BSO | MA, thiotepa | Died | No |
2 | Raju et al., 1985 [22] | 16 | right | lung | NS | not done | not done | Died | No |
3 | Tsujioka et al., 2003 [23] | 19 | left | lung | 110,000 | LSO, OM | EMA/CO | NED | Yes |
4 | Park et al., 2009 [24] | 55 | right | lung | 64,838 | TAH, BSO | BEP | NED | No |
5 | Gremeau et al., 2010 [25] | 46 | left | brain, lung | 4,962 | LSO | YES, details NS | Died | No |
6 | Exman et al., 2013 [26] | 24 | NS | lung | 675,713 | TAH, BSO, OM | BEP | NED | Yes |
7 | Rao et al., 2015 [27] | 26 | right | spleen, adrenal gland | 8,160 | RSO, OM, tumor resection of the spleen and adrenal gland | BEV | NED | No |
8 | Nishino et al., 2020 (present) | 38 | left | brain, lung | 5,030 | TAH, BSO, tumor resection of the lung | MEA, BEP, etc | Died | Yes |