Fig. 3

a-f Endometrioid adenocarcinoma of the cervix uteri with ovarian metastasis. Ovary (a-b): Cystic enlarged ovary showing extensive papillary and cribriform proliferations of an endometrioid adenocarcinoma (asterisk); Adjacent is a normal tube (a, arrow). Scale bars: a = 3 mm, b = 500 μm. Cervix (d-e): Adenocarcinoma with cribriform growth pattern (asterisk) in the endocervix next to normal endocervical glands (arrows). Scale bars: d = 500 μm, e = 200 μm. Consistent with HPV high-risk association the tumor shows strong immunohistochemical expression of p16 in the ovary (b) and in the endocervix (f). Scale bars: b and f = 500 μm